1992: The Cell Surface, Vol. LVII
Organizer: Bruce Stillman
Symposium Participants v Foreword xvii Receptors Receptors and Transmembrane Signaling B.L. Stoddard, H.-P. Biemann, and D.E. Koshland, Jr. 1 A Model for Transmembrane Signaling in a Bacterial Chemotaxis Receptor S.-H. Kim, G.G. Privé, J. Yeh, W.G. Scott, and M.V. Milburn 17 Receptor Protein-Tyrosine Kinases and Phosphatases T. Hunter, R.A. Lindberg, D.S. Middlemas, S. Tracy, and P. van der Geer 5The trk Family Tyrosine Kinases: Receptors for NGF-related Neurotrophins L.F. Parada, P. Tsoulfas, L. Tessarollo, J. Blair, S. Reid, and D. Soppet 43 Cloning and Analysis of Neurotrophic Factor Receptors Using Function-basedStrategies D.J. Glass, D.R. Gies, T. Stitt, S. Davis, P. Hantzopoulos, N.Y. Ip, M. Goldfarb, and G.D. Yancopoulos 53 Interactions of PDGF and FGF Receptors with Cytoplasmic Signaling Molecules K.G. Peters, J.A. Escobedo, W.J. Fantl, and L.T. Williams 63 Role of SH2-containing Proteins in Cellular Signaling by Receptor Tyrosine Kinases J. Schlessinger, M. Mohammadi, B. Margolis, and A. Ullrich 67 Phosphatidylinositol-3 Kinase and Growth Regulation S.P. Soltoff, C.L. Carpenter, K.R. Auger, R. Kapeller, B. Schaffhausen, and L.C. Cantley 75 The Type II TGF-b Receptor Signals Diverse Responses in Cooperation with the Type I Receptor J.L. Wrana, J. Carcamo, L. Attisano, S. Cheifetz, A. Zentella, F.López-Casillas, and J. Massagué 81 Protein Tyrosine Phosphatases: The Problems of a Growing Family N.K. Tonks, Q. Yang, A.J. Flint, M.F.B.G. Gebbink, B.R. Franza, Jr., D.E. Hill, H. Sun, and S. Brady-Kalnay 87 The Erythropoietin Receptor: Dimerization, Activation, and Tumorigenesis H.F. Lodish, D. Hilton, G. Longmore, S.S. Watowich, and A. Yoshimura 95 Regulation of Protein Tyrosine Kinase Activation by the T Cell Antigen Receptor z Chain A. Weiss, A.C. Chan, M. Iwashima, D. Straus, and B.A. Irving 107Activation of Immune System Effector Function by T-cell or Fc Receptor Intracellular Domains C. Romeo, W. Kolanus, M. Amiot, and B. Seed 117 G-Protein Coupled Receptors and Effectors G-Protein-coupled Receptors: Regulatory Role of Receptor Kinases and Arrestin Proteins R.J. Lefkowitz, J. Inglese, W.J. Koch, J. Ritcher, H. Attramadal, and M.G. Caron 127 Regulation of Mammalian Adenylyl Cyclases by G Protein a and bg Subunits W.-J. Tang, J.A. Iñiguez-Lluhi, S. Mumby, and A.G. Gilman 135 Detection of Coincident Signals by G Proteins and Adenylyl Cyclase H.R. Bourne, K.O. Lustig, Y.H. Wong, and B.R. Conklin 145 Thrombin Receptor Structure and Function S.R. Coughlin, R.M. Scarborough, T.-K.H. Vu, and D.T. Hung 149 Guanylyl Cyclases: Ligands and Functions T.D. Chrisman, S. Schulz, and D.L. Garbers 155 Lysophosphatidic Acid: A Novel Phospholipid with Hormone- and Growth Factor-like Activities W.H. Moolenaar, R.L. van der Bend, E.J. van Corven, K. Jalink, T.Eichholtz, and W.J. van Blitterswijk 163 G-Protein-linked Signaling Pathways Mediate Development in DictyosteliumR.L. Johnson, R. Gundersen, D. Hereld, G.S. Pitt, S. Tugendreich, C.L.Saxe, A.R. Kimmel, and P.N. Devreotes 169 Molecular Genetic Analysis of Signal Transduction Pathways Controlling Multicellular Development in Dictyostelium A.B. Cubitt, F. Carrel, S. Dharmawardhane, C. Gaskins, J. Hadwiger, P. Howard, S.K.O. Mann, K. Okaichi, K. Zhou, and R.A. Firtel 177 Adhesion Receptors Signaling between the Extracellular Matrix and the Cytoskeleton: Tyrosine Phosphorylation and Focal Adhesion Assembly L.H. Romer, K. Burridge, and C.E. Turner 193 Mechanisms of Fibronectin and Integrin Function during Cell Adhesion and Migration K.M. Yamada, S. Aota, S.K. Akiyama, and S.E. LaFlamme 203 Functional Roles for Integrin a-Subunit Cytoplasmic Domains M.E. Hemler, P.D. Kassner, and B.M.C. Chan 213 Ligand Binding to Integrins: Dynamic Regulation and Common Mechanisms M.H. Ginsberg, T.E. O'Toole, J.C. Loftus, and E.F. Plow 221 Role of aV Integrins and Vitronectin in Human Melanoma Cell Growth L.C. Sanders, B. Felding-Habermann, B.M. Mueller, and D.A. Cheresh 233 Genetic Interactions with Integrins during Wing Morphogenesis in Drosophila L.H.V. Wessendorf, M. Wehrli, A. DiAntonio, and M. Wilcox 241 Toward a Genetic Analysis of Cellular-Matrix Adhesion R.O. Hynes, E.L. George, E.N. Georges, J.-L. Guan, H. Rayburn, and J.T. Yang 249 Glycosylation-dependent Cell Adhesion Molecule 1: A Novel Mucin-like Adhesion Ligand for L-Selectin L.A. Lasky, M.S. Singer, D. Dowbenko, Y.Imai, W. Henzel, C. Fennie, S. Watson, and S.D. Rosen 259 Quantitative Determination of Selectin-Carbohydrate Interactions R.M. Nelson, A. Aruffo, S. Dolich, O. Cecconi, G. Mannori, and M.P. Bevilacqua 271 Molecular Mechanisms of Complex Carbohydrate Recognition at the Cell SurfaceW.I. Weis, M.S. Quesenberry, M.E. Taylor, K. Bezouška, W.A. Hendrickson,and K. Drickamer 281 Lymphocyte Homing Receptors M.C.-T. Hu, M.H. Siegelman, B. Holzmann, D.T. Crowe, and I.L. Weissman 291 Extracellular Matrix/Growth Factor Interactions E. Ruoslahti, Y. Yamaguchi, A. Hildebrand, and W.R. Border 309 Mediation and Inhibition of Cell Adhesion by Morphoregulatory Molecules G.M. Edelman 317 Cytoplasmic Control of Cadherin-mediated Cell-Cell Adhesions M. Takeichi, S. Hirano, N. Matsuyoshi, and T. Fujimori 327 Cadherins and the Morphogenesis of Epithelial Tissues in Xenopus Embryos C. Kintner 335 DCC: A Tumor Suppressor Gene Expressed on the Cell Surface L. Hedrick, K.R. Cho, J. Boyd, J. Risinger, and B. Vogelstein 345
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Development Intercellular Signaling during Caenorhabditis elegans Vulval Induction P.W. Sternberg, R.J. Hill, G. Jongeward, L.S. Huang, and L. Carta 353 Genes Involved in Two Caenorhabditis elegans Cell-signaling Pathways S.G. Clark, M.J. Stern, and H.R. Horvitz 363 Signal Transduction Pathway Initiated by Activation of the sevenless Tyrosine Kinase Receptor M.A. Simon, R.W. Carthew, M.E. Fortini, U. Gaul, G. Mardon, and G.M. Rubin 375 Induction of the R7 Neuron in the Drosophila Compound Eye: The bride of sevenless and sevenless Interaction S.L. Zipursky, H. Krämer, R. Cagan, A. Hart, and D. Van Vactor, Jr. 381 Delta, Notch, and shaggy, Elements of a Lateral Signaling Pathway in Drosophila P. Simpson, M. Bourouis, P. Heitzler, L. Ruel, M. Haenlin, and P. Ramain 391 Regulation of Induction by GLP1, a Localized Cell Surface Receptor in Caenorhabditis elegans J. Kimble, S. Crittenden, E. Lambie, V. Kodoyianni, S. Mango, and E. Troemel 401 Extracellular Morphogens in Drosophila Embryonic Dorsal-Ventral Patterning K.V. Anderson, D.S. Schneider, D. Morisato, and E.L. Ferguson 409 Neurobiology Adhesive Interactions That Regulate Development of the Retina and Primary Visual Projection L.F. Reichardt, B. Bossy, I. de Curtis, K.M. Neugebauer, K. Venstrom, and D. Sretavan 419 Second Messengers Underlying Cell-conact-dependent Axonal Growth Stimulated by Transfected N-CAM, N-cadherin, or L1 F.S. Walsh and P. Doherty 431 Development of Neuromuscular Specificity in Drosophila A. Nose, D. Van Vactor, V. Auld, and C.S. Goodman 441 Rostrocaudal Differences among Muscles Revealed by a Transgene: Graded Expression at Low Copy Number J.R. Sanes, M.J. Donoghue, M.C. Wallace, and J.P. Merlie 451 Agrin: A Synaptic Basal Lamina Protein That Regulates Development of the Neuromuscular Junction J.T. Campanelli, M. Ferns, W. Hoch, F. Rupp, M. von Zastrow, Z. Hall, and R. H. Scheller 461 Control of Floor Plate Identity and Function in the Embryonic Nervous System A. Klar, T.M. Jessell, and A. Ruiz i Altaba 473 Neurexins M. Geppert, Y.A. Ushkaryov, Y. Hata, B. Davletov, A.G. Petrenko, and T.C. Südhof 483 Elucidation of Biophysical and Biological Properties of Voltage-gated Potassium Channels T.J. Baldwin, E. Isacoff, M. Li, G.A. Lopez, M. Sheng, M.L. Tsaur, Y.N.Jan, and L.Y. Jan 491 Mechanisms of Sensitivity and Specificity in Olfaction R.R. Reed 501 The Molecular Biology of Smell: Expression of the Multigene Family Encoding Putative Odorant Receptors A. Chess, L. Buck, M.M. Dowling, R. Axel, and J. Ngai 505 Pharmacological and Genetic Approaches to the Analysis of Tyrosine Kinase Function in Long-term Potentiation T.J. O'Dell, S.G.N. Grant, K. Klar, P.M. Soriano, and E.R. Kandel 517 a Calcium/Calmodulin Kinase II Mutant Mice: Deficient Long-term Potentiation and Impaired Spatial Learning A.J. Silva, Y. Wang, R. Paylor, J.M. Wehner, C.F. Stevens, and S. Tonegawa 527 Structure and Interactions of CD4 S.C. Harrison, J. Wang, Y. Yan, T. Garrett, J. Liu, U. Moebius, and E. Reinherz 541 Structural Aspects of CD4 and CD8 Involvement in the Cellular Immune ResponseW.A. Hendrickson, P.D. Kwong, D.J. Leahy, S.-E. Ryu, H. Yamaguchi, S. Fleury, and R.-P. Sékaly 549 Biochemical Anatomy of Antigen Processing C.A. Nelson, C.V. Harding, and E.R. Unanue 557 MHC Products: Biosybthesis, Intracellular Traffic, and "Empty" Molecules H.L. Ploegh 565 Transport and Expression of Class I MHC Glycoproteins in an Antigen-processing Mutant Cell Line E.-M. Click, K.S. Anderson, M.J. Androlewicz, M.L. Wei, and P. Cresswell 571 Dedicated Transporters for Peptide Export and Intercompartmental Traffic in the Yeast Saccharpmyces cerevisiae K. Kuchler, H.M. Göransson, M.N. Viswanathan, and J. Thorner 579 Membrane Traffic and Cytoskeletal Assembly Each Caveola Contains Multiple Glycosyl-Phosphatidylinositol Anchored Membrane Proteins Y.-S. Ying, R.G.W. Anderson, and K.G. Rothberg 593 Molecular Flypaper, Atherosclerosis, and Host Defense: Structure and Function of the Macrophage Scavenger Receptor M. Krieger, J.M. Abrams, A. Lux, and H. Steller 605 Biogenesis of Cell-Surface Polarity in Epithelial Cells and Neurons K. Simons, P. Dupree, K. Fiedler, L. Huber, T. Kobayashi, T. Kurzchalia, V. Olkkonen, S. Pimplikar, R. Parton, and C. Dotti 611 Regulation of Epithelial Cell Polarity: A View from the Cell Surface W.J. Nelson, R. Wilson, D. Wollner, R. Mays, H. McNeill, and K. Siemers 621 Cytoplasmic Control of Cell Adhesion B. Geiger, O. Ayalon, D. Ginsberg, T. Volberg, J.L. RodrÃÂguez Fernández Y. Yarden, and A. Ben-Ze'ev 631 Desmosomal Proteins: Mediators of Intercellular Coupling and Intermediate Filament Anchorage W.W. Franke, S.M. Troyanovsky, P.J. Koch, R. Troyanovsky, B. Fouquet, and R. E. Leube 643 Role of the Zygotic Genome in the Restructuring of the Actin Cytoskeleton at the Cycle-14 Transition during Drosophila Embryogenesis E.D. Schejter, L.S. Rose, M.A. Postner, and E. Wieschaus 653 Distinct Patterns of Actin Organization Regulated by the Small GTP-binding Proteins Rac and Rho A.J. Ridley and A. Hall 661 Summary: The Cell Surface Regulates Information Flow, Material Transport, and CellIdentity M.I. Simon 673
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