1983: Molecular Neurobiology, Vol. XLVIII
Organizer: J.D. Watson, R. McKay
Symposium Participants v Foreword xiiiPart 1Acetyicholine Receptor and Its ChannelThe Arrangement and Functions of the Chains of the Acetylcholine Receptor of Torpedo Electric Tissue A. Karlin, R. Cox, R. -R. Kaldany, P. Lobel, and E. Holtzman 1Subunit Organization and Structure of an Acetylcholine Receptor R. H. Fairclough, J. Finer-Moore, R. A. Love, K. Krisrofferson, P. J. Desmeules, and R, .M. Stroud 9The Nicotinic Acetylcholine Receptor: Subunit Structure, Functional Binding Sites, and Ion Transport Properties M .A. Raftery, S.M.J. Dunn, B. M. Conti-Tronconi, D. S. Middlemas, and R.. D. Crawford 21Allosteric Properties of the Acetyicholine Receptor Protein from Torpedo mar- morata J.-P. Changeux, F. Bon, J. Cartaud, A. Devillers-Thiéry, J. Giraudat, T. Heidmann, B. Holton, H. -O. Nghhiêm, J. -L. Popot, R. Van Rapenbusch, and S. Tzartos 35Muscarinic Receptor Subclasses: Allosteric Interactions N.J.M. Birdsall, E. C. Hulme, and J. M. Stockton 53Molecular Structure of the Nicotinic Acetylcholine Receptor S. Numa, M. Noda, H. Takahashi, T. Tanabe, M. Toyosato, Y. Furutani, and S. Kikyotani 57Molecular Cloning of the Acetylcholine Receptor J. Patrick, M. Ballivet, L. Boas, T. Claudio, J. Forrest, H. Ingraham, P. Mason, S. Stengelin, S. Ueno, and S. Heinemann 71Structure and Expression of Genomic Clones Coding for the d-Subunit of the Torpedo Acetylcholine Receptor N. D. Hershey, D. J. Noonan, K. S. Mixter, T. Claudio, and N. Davidson 79Genomic Sequences Encoding the a-Subunit of Acetylcholine Receptor Are Conserved in Evolution M. Ballivet, P. Nef, R. Stalder, and B. Fulpius 83Use of Monoclonal Antibodies to Study Acetylcholine Receptors from Electric Organs, Muscle, and Brain and the Autoimmune Response to Receptor in Myasthenia Gravis J. Lindstrom, S. Tzartos, W. Gullick, S. Hockschwender, L. Swanson, P. Sargent, M. Jacob, and M. Montal 89A Developmental Change in the Immunological Properties of Acetylcholine Receptors at the Rat Neuromuscular Junction Z. W. Hall, M. -P. Roisin, Y. Gu, and P.D. Gorin 101Acetyicholine and GABA Receptors: Subunits of Central and Peripheral Receptors and Their Encoding Nucleic Acids E.A. Barnard, D. Beeson, G. Bilbe, D.A. Brown, A. Constanti, B.M. Conti-Tronconi, J.O. Dolly, S.M.J. Dunn, F. Mehraban, B.M. Richards, and T.G. Smart 109Molecular Events in the Synthesis and Assembly of a Nicotinic Acetylcholine Recep- tor D.J. Anderson and G. Blobel 125The Regulation of Acetylcholine Receptor Expression in Mammalian Muscle J. P. Merlie, R. Sebbane, S. Gardner, E. Olson, and J. Lindstrom 135Sodium ChannelInactivation of Open and Closed Sodium Channels Determined Separately R. W. Aldrich and C. F. Stevens 147Structure and Functional Reconstitution of the Voltage-sensitive Sodium Channel from Rat Brain J.A. Talvenheimo, M.M. Tamkun, R.P. Hartshorne, D.J. Messner, R.G. Sharkey, M.R.C. Costa, and W.A. Catterall 155The Voltage-regulated Sodium Channel from the Electroplax of Electrophorus elec- tricus W. S. Agnew, J.A. Miller, M. H. Ellisman, R.L. Rosenberg, S.A. Tomiko, and S.R. Levinson 165Immunochemical Studies of the Voltage-sensitive Sodium Channel from the Electroplax of the Eel Electrophorous electricus L. C. Fritz, H. -P. H. Moore, M. A. Raftery, and J. P. Brockes 181The Molecular Mechanism of Action of the b-Adrenergic Receptor M. Schramm, M. Korner, G. Neufeld, and E. Nedivi 187 Calcium and Potassium ChannelsModulation of Calcium Channels in Cultured Cardiac Cells by Isoproterenol and 8-Bromo-cAMP H. Reuter, A.B. Cachelin, I.E. De Peyer, and S. Kokubun 193Calcium Channels: Mechanisms of b-Adrenergic Modulation of Ion Permeation R. W. Tsien, B.P. Bean, P. Hess, and M. Nowycky 201Modulation of a Specific Potassium Channel in Sensory Neurons of Aplysia by Serotonin and cAMP-dependent Protein Phosphorylation J.S. Carmardo, M.J. Shuster, S.A. Siegelbaum, and E.R. Kandel 213Genetic and Voltage-clamp Analysis of a Drosophila Potassium Channel L. Salkoff 221Mutating a Gene for a Potassium Channel by Hybrid Dysgenesis: An Approach to the Cloning of the Shaker Locus in Drosophila L. Y Jan, S. Barbel, L. Timpe, C. Laf- fer, L. Salkoff, P. O'Farrell, and Y. N. Jan 233Ion Transport by Single Receptor Channels B. Sakmann, J. Bormann, and O.P. Hamill 247Excitable Membrane Properties of Cultured Central Nervous System Neurons and Clonal Pituitary Cells J. L. Barker, B. Dufy D. G. Owen, and M. Segal 259Glutamate- and GABA-receptor Channels at the Locus Nerve-Muscle Junction: Noise Analysis and Single-channel Recording S. G. Cull-Candy 269Chemical and Pharmacological Approaches to the Definition and Quantitation of Calcium Channels P.J. Gengo, E. Lochowski, D. E. Rampe, A. Rutledge, A. M. Triggle, D.J. Triggle, and R.A. Janis 279Purification and Characterization of ATP-dependent Calcium Pumps from Synap- tosomes S.M. Goldin, S. Y Chan, D.M. Papazian, E.J. Hess, and H. Rahamimoff 287Studies of the Na+ -K + ATPase of Skeletal Muscle and Nerve D. M. Fambrough 297Studies on Neuronal Proteins with Recombinant DNA TechniquesDetection and Regulation of the Tyrosine Hydroxylase mRNA Levels in Rat Adrenal Medulla and Brain Tissues J. Mallet, N. Faucon Biguet, M. Buda, A. Lamouroux, and D. Samolyk 305Cloning and Characterization of Rat-brain-specific Transcripts: Rare, Brain-specific Transcripts and Tyrosine Hydroxylase D.M. Chikaraishi, M.H. Brilliant, and E.J. Lewis 309Dopamine-b-Hydroxylase Rat mRNA: Structure, Regulation, and Tissue Localiza- tion K. O'Malley, A. Mauron, G. Makk, D.L. Wong, R.D. Ciaranello, J.D. Barchas, and L. Kedes 319Evidence for the Existence of Homologous Gene Coding Regions for the Catecholamine Biosynthetic Enzymes T.H. Joh, E.E. Baetge, M.E. Ross, and D.J. Reis 327Neuron-specific Phosphoproteins as Models for Neuronal Gene Expression L.J. DeGennaro, S.D. Kanazir, W. C. Wallace, R.M. Lewis, and P. Greengard 337Expression of Cell-type-specific Neuronal Phosphoproteins R.M. Lewis, W. C. Wallace, S.D. Kanazir, and P. Greengard 347Studies on Voltage-operated Calcium Channels Using Radioligands R.J. Gould, K.M.M. Murphy, and S.H. Snyder 355Molecular Aspects of NeuropeptidesPeptides in Neuronal Function-Studies Using Frog Autonomic Ganglia Y.N. Jan, C. W. Bowers, D. Branton, L. Evans, and L. Y. Jan 363Generation of Diversity and Evolution of Opioid Peptides E. Herbert, E. Oates, G. Martens, M. Comb, H. Rosen, and M. Uhler 375Analysis of POMC Gene Expression by Transcription Assay and In Situ Hybridization Histochemistry J. L. Roberts, J. H. Eberwine, and C. E. Gee 385The Enkephalinergic Neuron: Implications of a Polyenkephalin Precursor J. Rossier, D. Liston, G. Patey, M. Chaminade, A.S. Foutz, A. Cupo, P. Giraud, M.P. Roisin, J. P. Henry, P. Verbanck, and J.-J. Vanderhaeghen 393The Molecular Basis of a Neuroendocrine Fixed Action Pattern: Egg Laying in Aplysia A..C. Mahon and R. H. Scheller 405Molecular Events in Developmental Regulation of Neuroendocrine Genes- Characterization of the Novel Neuropeptide CGRP R..M. Evans, S. Amara, and M. G. Rosenfeld 413The Kallikrein Multigene Family: Specific Processing of Biologically Active Pep- tides J. Shine, A..J. Mason, B.A. Evans, and R..I. Richards 419The Biosynthesis and Processing of Proteins in the Mouse 7S Nerve Growth Factor Complex T.L.J. Darling, P.E. Petrides, P. Beguin, P. Frey, E.M. Shooter, M. Selby, and W.J. Rutter 427Sequence Homology of Human and Mouse b-NGF Subunit Genes A. Ullrich, A. Gray, C. Berman, L Coussens, and T.J. Dull 435
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Part 2 Genetic Analysis of the Nervous System Neuronal Cell Lineages in the Nematode Caenorhabditis elegans J.E. Sulston 443 Mutations That Affect Neural Cell Lineages and Cell Fates during the Development of the Nematode Caenorhabditis elegans H.R. Horvitz, P. W Steinberg, I.S. Green- wald, W. Fixsen, and H.M. Ellis 453 Genetic Expression and Postnatal Development of the Brain: Some Characteristics of Nonpolyadenylated mRNAs W.E. Hahn, N. Chaudhari, L. Beck, K. Wilber, and D. Peffley 465 Cellular Localization and Function of the Proteins Encoded by Brain-specific mRNAs J. G. Sutcliffe, R..J. Milner, and F.E. Bloom 477 Gene Expression and the Diversity of Identified Neurons L. Buck, R. Stein, M. Palaz- zolo, D. Anderson, and R. Axe 485 Chromatin Changes Accompanying Neuronal Differentiation C. C. Kuenzle, C. W. Heiz- mann, U.Hübscher, R. Hobi, G. C. Winkler, A. W. Jaeger, and G. Morgenegg 493 Neuronal Surface Molecules Molecular and Biological Properites of a Neural Cell Adhesion Molecule U. Rutishauser 501 Structure and Modulation of Neural Cell Adhesion Molecules in Early and Late Em- bryogenesis G.M. Edelman, S. Hoffman, C.-M. Chuong, J.-P. Thiery, R. Brackenbury, W.J. Gallin, M. Grumet, M.E. Greenberg, J.J. Hemperly, C. Cohen, and B.A. Cunningham 515 Neural Surface Antigens during Nervous System Development C. Goridis, H. Deagostini-Bazin, M. Hirn, M.-R. Hirsch, G. Rougon, R. Sadoul, O.K. Langley, G. Gombos, and J. Finne 527 The Structure and Function of Myoblast Adherons D. Schubert, M. LaCorbiere, F. G. Klier, and C. Birdwell 539 Do Monoclonal Antibodies Stain Sets of Functionally Related Leech Neurons? B. Zipser, R. Stewart, T. Flanagan, M. Flaster, and E.R. Macagno 551 Cell-type Specificity and Developmental Expression of Neural Cell-surface Components Involved in Cell Interactions and of Structurally Related Molecules M. Schachner, A. Faissner, J. Kruse, J. Lindner, D. H. Meier, F. G. Rathjen, and H. Wernecke 557 Glial Cell Lineages in the Rat Optic Nerve M. C. Raff, R. H. Miller, and M. Noble 569 The Regulation of Axon Organization Navigational Substrates for Peripheral Pioneer Growth Cones: Limb-axis Polarity Cues, Limb-segment Boundaries, and Guidepost Neurons D. Bentley and M. Caudy 573 Guidance of Neuronal Growth Cones: Selective Fasciculation in the Grasshopper Em- bryo J.A.. Raper, M.J. Bastiani, and C..S. Goodman 587 The Molecular Organization of the Leech Nervous System R..D. McKay, S. Hockfield, J. Johansen, and K. Frederiksen 599 Studies on Extracellular Matrix Components That Promote Neurite Outgrowth A. D. Lander, K Tomaselli, A.L. Calof, and L.F. Reichardt 611 The Production of a Monoclonal Antibody That Blocks the Action of a Neurite Outgrowth-promoting Factor W. D. Matthew and P. H. Patterson 625 Factors That Determine Connectivity in the Nervous System of C. elegans J. G. White, E. Southgate, J.N. Thomson, and S. Brenner 633 What Genes Are Necessary to Make an Identified Synapse? R.J. Wyman and J.B. Thomas 641 Synaptic Organization and Function Molecular Components of the Synaptic Basal Lamina That Direct Differentiation of Regenerating Neuromuscular Junctions R.M. Nitkin, B. G. Wallace, M.E. Spira, E. W. Godfrey, and U.J. McMahan 653 The Basal Lamina of the Neuromuscular Junction J. R. Sanes and A. Y. Chiu 667 Quantitation and Purification of Neurotrophic Molecules H. Thoenen, S. Korsching, Y-A. Barde, and D. Edgar 679 Cytochemical and Physiological Properties of Sensory and Dorsal Horn Neurons That Transmit Cutaneous Sensation J. Dodd, C.E. Jahr, P.N. Hamilton, M.J.S. Heath, W.D. Matthew, and T.M. Jessell 685 Membrane Traffic in Neurons and Peptide-secreting Cells R. B. Kelly, K. M. Buckley, T.L. Burgess, S.S. Carlson, P. Caroni, J.E. Hooper, A. Katzen, H.-P. Moore, S.R. Pfeffer, and T.A. Schroer 697 Synapse Formation by Neuroblastoma Hybrid Cells M. Nirenberg, S. Wilson, H. Higashida, A. Rotter, K. Krueger, N. Busis, R. Ray, K. Kenimer, M. Adler, and H. Fukui 707 The Cellular Organization of Neurons Neurofilaments, a Subclass of Intermediate Filaments: Structure and Expression K. Weber, G. Shaw, M. Osborn, E. Debus, and N. Geisler 717 Molecular Biology of Neuronal Geometry: Expression of Neurofilament Genes In- fluences Axonal Diameter R.J. Lasek, M. M. Oblinger, and P. F. Drake 731 Polyribosomes at the Base of Dendritic Spines of Central Nervous System Neurons- Possible Role in Synapse Construction and Modification O. Steward 745 Cell-surface Molecules That Characterize Different Stages in the Development of Cerebellar Interneurons W.B. Stallcup, L. Beasley, and J. Levine 761 Neuronal Microdifferentiation A. Matus, G. Huber, and R. Bernhardt 775 Expression of mRNA for Microtubule Proteins in the Developing Nervous System I. Ginzburg, T. Scherson, S. Rybak, Y. Kimhi, D. Neuman, M. Schwartz, and U.Z. Littauer 783 Axonally Transported Proteins in Axon Development, Maintenance, and Regenera- tion C. Baitinger, R. Cheney, D. Clements, M. Glicksman, N. Hirokawa, J. Levine, K. Meiri, C. Simon, P. Skene, and M. Willard 791 Behavior Bacterial Chemotaxis and Molecular Neurobiology J. Adler 803 Information Processing in a Sensory System D. E. Koshland, Jr., A. F. Russo, and N.I. Gutterson 805 What Molecular Steps Determine the Time Course of the Memory for Short-term Sen- sitization in Aplysia? J. H. Schwartz, L. Bernier, V. F. Castellucci, M. Pala
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