1961: Cellular Regulatory Mechanisms, Vol. XXVI
Organizer: Arthur Chovnick
Foreword v List of Previous Volumes vi Photographs of Some Participants viiList of Those Attending the Symposium ix OPENING ADDRESSDAVIS, B. D. The, Teleonomic Significance of Biosynthetic Control Mechanisms 1 THE ROLE OF DNA IN PROTEIN SYNTHESIS YANOFSKY, C., D. R. HELINSKI, AND B. D. MALING. The Effects of Mutation on the Composition and Properties of the A Protein of Escherichia coli Tryptophan Synthetase 11 STREISINGER, G., F. MUKAI, W. J. DREYER, B. MILLER, AND S. HORIUCHI. Mutations Affecting the Lysozyme of Phage T4 25 SIGNER, E. R., A. TORRIANI, AND C. LEVINTHAL. Gene Expression in Intergeneric Merozygotes 31 SUEOKA, N. Compositional Correlation between Deoxyribonucleic Acid and Protein 35 THE CONTROL OF NUCLEIC ACID SYNTHESIS MAALØE, O. The Control of Normal DNA Replication in Bacteria 45 SCHAECHTER, M. Patterns of Cellular Control during Unbalanced Growth 53 NEIDHARDT, F. C., AND D. G. FRAENKEL. Metabolic Regulation of RNA Synthesis in' Bacteria 63 THE ROLE OF DNA IN RNA SYNTHESIS SPIEGELMAN, S. The Relation of Informational RNA to DNA 75 HURWITZ, J., J. J. FURTH, M. ANDERS, P. J. ORTIZ, AND J. T. AUGUST. The Enzymatic Incorporation of Ribonucleotides into RNA and the Role of DNA 91 THE ROLE OF RNA IN PROTEIN SYNTHESIS BRENNER, S. RNA, Ribosomes, and Protein Synthesis 101 GROS, F., W. GILBERT, H. H. HIATT, G. ATTARDI, P. F. SPAHR, AND J. D. WATSON. Molecular and Biological Characterization of Messenger RNA 111 NOVELLI, G. D., T. KAMEYAMA, AND J. M. EISENSTADT. The Nature of the System Catalyzing the Synthesis of Induced b-Galactosidase 133 NISMAN, B., R. COHEN, A. KAYSER, H. FUKUHARA, J. DEMAILLY, C. GENIN, AND D. GIRON. Specific Protein Synthesis in Subcellular Systems of Escherichia coli 145 HOAGLAND, M. Some Factors Influencing Protein Synthetic Activity in a Cell-Free Mammalian System 153 PLESNER, P. Changes in Ribosome Structure and Function during Synchronized Cell Division 159 REGULATION OF ENZYME SYNTHESIS VOGEL, H. J. Aspects of Repression in the Regulation of Enzyme Synthesis: Pathway-wide Control and Enzyme-specific Response 163 GORINI, L., W. GUNDERSEN, AND M. BURGER. Genetics of Regulation of Enzyme Synthesis in the Arginine Biosynthetic Pathway of Escherichia coli 173 MAAS, W. K. Studies on Repression of Arginine Biosynthesis in Escherichia coli 183 JACOB, F. AND J. MONOD. On the Regulation of Gene Activity 193 BUTTIN, G. Some Aspects of Regulation in the Synthesis of the Enzymes Governing Galactose Metabolism 213
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YARMOLINSKY, M. B., E. JORDAN, AND H. WIESMEYER. Regulatory Mechanisms in the Synthesis of Enzymes of Galactose Metabolism. I. Coordinate Repression and De-Repression of the "Galactose Sequence." 217 KALCKAR, H. AND T. A. SUNDARARAJAN. Regulatory Mechanisms in the Synthesis of Enzymes of Galactose Metabolism. II. Genetic Defects in Galactokinase Activity and Their Relations to its Functions 227 HOROWITZ, N. H., M. FLING, H. MACLEOD, AND Y. WATANABE. Structural and Regulative Genes Controlling Tyrosinase Synthesis in Neurospora 233 NOVICK, A. AND a'. HORIUCHI. Hyper-Production of b-Galactosidase by Escherichia coli Bacteria 239HORIUCHI, T. AND A. NOVICK. A Thermolabile Repression System 247 MAGASANIK, B. Catabolite Repression 249 KORNBERG, H. L. Selective Utilization of Metabolic Routes by Escherichia coli 257 ENGLESBERG, E., J. A. WATSON, AND P. A. HOFFEE. The Glucose Effect and the Relationship between Glucose Permease, Acid Phosphatase, and Glucose Resistance 261 CONTROL OF ENZYME ACTIVITY: COMPETITION BETWEEN ENZYMES HOLZER, H. Regulation of Carbohydrate Metabolism by Enzyme Competition 277 CHANCE, B. Control Characteristics of Enzyme Systems 289 CONTROL OF ENZYME ACTIVITY: FEEDBACK CONTROL UMBARGER, H. E. Feedback Control by Endproduct Inhibition 301 CHANGEUX, J. The Feedback Control Mechanism of Biosynthetic L-Threonine Deaminase by L-Isoleucine 313 STADTMAN, E. R., G. N. COHEN, G. LE BRAS, AND H. DE ROBICHON-SZULMAJSTER. Selective Feedback Inhibition and Repression of Two Aspartokinases in the Metabolism of Escherichia coli 319 MOYED, H. S. Interference with Feedback Control of Enzyme Activity 323 CONTROL OF ENZYME FORMATION AND ACTIVITY IN ANIMAL SYSTEMS TOMKINS, G. M. AND K. L. YIELDING. Regulation of the Enzymic Activity of Glutamic Dehydrogenase Mediated by Changes in its Structure 331 MARKS, P. A. Glucose-6P Dehydrogenase Stability, Activation, and Inactivation 343 RALL, T. W. AND E. W. SUTHERLAND. The Regulatory Role of Adenosine-3', 5'-phosphate 347 POTTER, V. R. AND T. ONO. Enzyme Patterns in Rat Liver and Morris Hepatoma 5123 During Metabolic Transitions 355 SCHIMKE, R. T. Studies on Adaptation of Urea Cycle Enzymes in the Rat 363 HIATT, H. H. AND T. B. BOJARSKI. The Effects of Thymidine Administration on Thymidylate Kinase Activity and on DNA Synthesis in Mammalian Tissues 367 PITOT, H. C. AND Y. S. CHO. Studies on the Mechanism of Enzyme Induction' in Rat Liver 371 BAKEMEIER, R. A Possible Cellular Explanation of the Multiplicity of Steroid Reductases 379 GENERAL CONCLUSIONS MONOD, J. AND JACOB, F. Teleonomic Mechanism in Cellular Metabolism, Growth, and Differentiation 389
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